Identification of Wake-Active Dopaminergic Neurons in the Ventral Periaqueductal Gray Matter
نویسندگان
چکیده
منابع مشابه
Identification of wake-active dopaminergic neurons in the ventral periaqueductal gray matter.
Recent evidence suggests that dopamine plays an important role in arousal, but the location of the dopaminergic neurons that may regulate arousal remains unclear. It is sometimes assumed that the dopaminergic neurons in the ventral tegmental area that project to the prefrontal cortex and striatum may regulate the state of arousal; however, the firing of these dopaminergic neurons does not corre...
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متن کاملEbf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.
Dopaminergic (DA) neurons in the midbrain ventral periaqueductal gray matter (PAG) play critical roles in various physiological and pathophysiological processes including sleep-wake rhyme, antinociception, and drug addiction. However, the molecular mechanisms underlying their development are poorly understood. Here, we showed that PAG DA neurons arose as early as E15.5 in mouse embryos. During ...
متن کاملSaccade-related activity of periaqueductal gray matter of the monkey.
Single unit activity was recorded extracellularly from the periaqueductal gray matter (PAG) and the superior colliculus of three monkeys during spontaneous saccades and fixation. Most saccade-related cells were found in the dorsal and lateral regions of the PAG and they paused with saccades. The pause preceded the onset of saccades by 34.5 +/- 6.8 msec (n = 31). In 90% of the 31 PAG cells, the ...
متن کاملIdentification of discrete functional subregions of the human periaqueductal gray.
The midbrain periaqueductal gray (PAG) region is organized into distinct subregions that coordinate survival-related responses during threat and stress [Bandler R, Keay KA, Floyd N, Price J (2000) Brain Res 53 (1):95-104]. To examine PAG function in humans, researchers have relied primarily on functional MRI (fMRI), but technological and methodological limitations have prevented researchers fro...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2006
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.2244-05.2006